AIIMS NOV 2008

In an emphysematous patient with [bleep] lesion which is the best investigation to measure lung volumes?
A. Body plethysmography
b. Helium dilution
c. Trans diaphragmatic pressure
d. DLCO

ans a
A 9 yr old girl has difficulty in combing hairs and climbing upstairs since 6 months. She has Gowers sign positive and maculopapular rash over metacarpo phalangeal joints. What should be the next appropriate investigation to be done?
A. ESR
b. RA factor
c. Creatine kinase
d. Electromyography
ans c
2.antibody found in myositis is?
A. Anti jo1
b anti scl 70
c. Anti ds dna
d.anti sm antibody
ans a
3. A girl on exposure to cold has pallor of extremities followed by pain and cyanosis. In later ages of life she is prone to develop?
A. SLE
b. Scleroderma
c. Rheumatoid arthritis
d. systemic sclerosis
ans b
4. Which radiological feature would help differentiate rheumatoid arthritis with SLE?
A. Erosion
b. Juxta articular osteoporosis
c. Subluxation of MCP joint
d. Swelling of pip joint
ans a
5.all are seen in Reiters syndrome except?
A. Subcutaneous nodules
b. Oral ulcers
c. Keratoderma belanorrhagicum
d. Circinate balanitis
ans a
6.which of the organism causes reactive arthritis?
A. Ureaplasma urealyticum
b. Group a beta hemolytic streptococci
c. Borrelia burgdorferi
d. Nocadia
ans a

7.All is true about metachromatic leucodystrophy except?
A. Follows an indolent course and slow to progress
b. Tissue biopsy is diagnostic
c. Presents as visual loss and speech abnormality
d. Involves deep cortical neurons
ans d

8. Most common cause of mononeuritis multiplex in india is?
A. Hansens disease
b. Rheumatoid arthritis
c. Tuberculosis
d. Polyarteritis Nodosa
ans a
9.wiskott aldrich syndrome is characterised by all except?
A. Thrombocytopenia
b. Autosomal recessive
c. Failure of aggregation of platelets in response to agonists
d. Eczema
ans b
10.spontaneous CSF leak occurs in all except?
A. Increased ICT
b. Partial or complete empty sella syndrome
c. Pseudotumour cerebri
d. Low risk encephalocoele
ans c
11. True about fluorescent antibody detection test in diagnosis of plasmodium falcifarum are a/e?
A. It’s an immunochromatic test
b. Detection of histidine rich protein 1
c. Detection of lactate dehydrogenase antigen
d. Detection of aldolase antigen
ans b
12.microangiopathic hemolytic anemia is seen in a/e?
A. Antiphosphplipid antibody syndrome
b. Thrombotic thrombocytopenic purpura
c. Microscopic polyangitis
d. Metallic cardiac valves
ans a
13. Which of these is not a marker of active replicative phase of chronic hepatitis B?
A. Anti-HBs Ag
b. Hbv DNA polymerase
c. Anti HBc
d. AST and ALT
ans a
14.vasodialation in spider naevi is due to?
A. Hepato-toxin
b. Estrogen
c. Testosterone
d. DHEA
ans b

16.a 29 yr old unmarried female presents with dyspnea, her chest x ray is normal, fvc-92% fevi/fvc-89% dlco-59%. On exercise her oxygen saturation drops from 92% to 86%. What is the diagnosis?
A. Alveolar hypoventillation
b. Primary pulmonary hypertension
c. Interstitial lung disease
d. Anxiety
ans c
17. A man on 10 days course of cephalosporins on 8th day of treatment develops high-grade fever and rashes all over the body. What is the diagnosis?
A. Partially treated meningitis
b. Type iii hypersensitivity reaction
c. Kawasaki’s ds
d. @@@
ans b
18. Which is false about acrodermatitis enteropathica?
A. Triad of Diarrhoea dementia dermatitis
b. Low serum zinc levels
c. Symptoms improve with zinc supplementation
d. perianal Rash
ans a
19.which of the following is not a minor criteria for multiple myeloma?
A. Multiple lytic bone lesions
b. Plasmacytosis of 20% in bone marrow
c. Plasmacytoma on tissue biopsy
d. Residual IgM level less than 50 mg/dL
ans b
20.which of the following features of uremia will not improve with hemodialysis?
A. Peripheral neuropathy
b. Pericarditis
c. Seizures
d. Metabolic acidosis
ans a
21.not a major Framingham criteria for diagnosis of congestive Heart failure?
A. Hepatomegaly
b. Cardiomegaly
c. S3 gallop
d. Paroxysmal nocturnal dyspnea
ans a
22.a 54 yr old smoker man comes with fever hemoptysis weight loss and oligo-arthritis. Serial skiagram shows fleeting opacities. What is the diagnosis?
A. Allergic bronchopulmonary aspergillosis
b. Ca lung
c. Tuberculosis
d. Wegeners granulomatosis
ans a
23.Misfolded proteins are seen in a/e?
A. Prion disease
b. Multiple sclerosis
c. Amyloidosis
d. Creutzfeldt jacob disease

ans c
157. A 7 yr old girl with non-productive cough, mild stridor for 3 months duration. Patient is improving but suddenly developed wheeze productive cough mild fever and hyperlucency on cxr and pft shows obstructive curve.diagnosis is?
A. Bronchiolitis obliterans
b. Hemosiderosis
c. Pulmonary alveolar microlithiasis
d. Follicular bronchitis
ans c
158. 3.5 kg term male baby born of uncomplicated pregnancy developed respiratory distress at birth not responded to surfactant, echo is normal, CXR shows ground glass appearance. Culture negative. Apgar score 4 and 5 at 1 and 5 min. and a history of 1-month female sibling died before diagnosis?
A. TAPVC
b. Meconium aspiration
c. Neonatal plmonary alveolar proteinosis
d. Diffuse herpes simplex infection
ans c
159. All are true about congenital rubella except?
A. Igg persists for more than 6 months
b. Igm antibody is present at birth
c. Most common anomalies are hearing and heart defects
d. Increased congenital malformation if infection after 16 weeks
ans d
160. A 10 yr old child is always restless inattentive to study and always wants to play outside. Parents are extremely distressed. What would you advise?
A. It’s a normal behaviour
b. Behaviour therapy
c. It’s a serious illness requires medical treatment
d. Needs change in environment
ans b
161.a 2yr old child brought to emergency at 3 am. Child has barky cough and stridor only while crying. Normal hydration RR -36/min temp -39.6 Degrees Celsius. What will be your next step?
A. Racemic epinephrine nebulisation
b. High dose dexamethasone inj
c. Nasal was for influenza/rsv
d. Antibiotics and blood culture
ans b
162.Bad prognostic factor for acute lymbhoblastic leukemia is?
A. Age 2-8 years
b. TLC <50000
c. Hyperdiploidy
d. T (9:22), t( 8:14),t(4:11)

ans d